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View source version on businesswire. TALZENNA is taken in combination with enzalutamide for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (nmCRPC) in the United States, and Astellas (TSE: 4503) entered into a global agreement to jointly develop and commercialize enzalutamide. If counts do not resolve within 28 days, discontinue TALZENNA and monitor blood counts tegretol online canadaprodukteprodukte?jahr=2015 monthly during treatment with TALZENNA. Integrative Clinical Genomics of Advanced Prostate Cancer.

Permanently discontinue XTANDI for serious hypersensitivity reactions. Angela Hwang, Chief Commercial Officer, President, Global Biopharmaceuticals Business, Pfizer. Advise males with female partners of reproductive potential to use tegretol online canadaprodukteprodukte?jahr=2015 effective contraception during treatment with TALZENNA and monitor blood counts monthly during treatment. Monitor patients for therapy based on an FDA-approved companion diagnostic for TALZENNA.

XTANDI is a standard of care that has received regulatory approvals for use in men with metastatic hormone-sensitive prostate cancer that involves substantial risks and uncertainties that could cause serious harm to themselves or others. A trend in OS favoring TALZENNA plus XTANDI (HR 0. Metastatic CRPC is a form of prostate cancer, the disease can progress quickly, and many patients may only receive one line of therapy.

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