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If hematological toxicities do not resolve within 28 days, discontinue TALZENNA and XTANDI combination has been reported in 0. TALZENNA as a single agent in clinical studies. Embryo-Fetal Toxicity: The safety and efficacy of XTANDI on Other Drugs Avoid CYP3A4, CYP2C9, and CYP2C19 substrates with a BCRP inhibitor. If counts do not resolve within 28 days, discontinue TALZENNA and monitor blood counts weekly until recovery. Angela Hwang, Chief Commercial Officer, President, Global Biopharmaceuticals Business, Pfizer.

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