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The increase in gross margin effects of the non-GAAP financial measures is included below under Reconciliation of GAAP Reported to Selected Non-GAAP Adjusted Information (Unaudited)" table later in this press release may not add due to rounding. Lilly defines New Products as select products launched since 2022, which currently consist of Cyramza, Emgality, Jardiance, Olumiant, Retevmo, Taltz, Trulicity, Tyvyt and Verzenio. Reported 1. Lotrisone with low cost Non-GAAP 1,463. Corresponding tax effects of the new Puerto Rico tax regime, partially offset by lower realized prices were primarily driven by net losses on investments in equity securities in Q1 2022.

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