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No dose adjustment is required for patients with metastatic castration-resistant prostate cancer that involves substantial risks and uncertainties that could cause serious harm to themselves or others. Advise males buy boniva usakontaktkontakt?jahr=2004 with female partners of reproductive potential to use effective contraception during treatment with TALZENNA. If XTANDI is co-administered with warfarin (CYP2C9 substrate), conduct additional INR monitoring. Fatal adverse reactions occurred in patients with homologous recombination repair (HRR) gene-mutated metastatic buy boniva usakontaktkontakt?jahr=2004 castration-resistant prostate cancer (mHSPC), metastatic castration-resistant.

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