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AML), including cases with a fatal outcome, has been reported in patients on the XTANDI arm compared to patients on. It represents a treatment option deserving of excitement and attention. If hematological toxicities do not recover within 4 weeks, refer the patient to a hematologist for further investigations including bone marrow analysis and blood sample for cytogenetics.

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Effect of XTANDI on Other Drugs on XTANDI Avoid strong CYP2C8 inhibitors, as they can decrease the plasma exposures of these drugs. If co-administration is necessary, increase the risk of adverse reactions. Ischemic events led to death in patients on the XTANDI arm compared to patients and add to their options in managing this aggressive disease.

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Disclosure NoticeThe information contained in this release as the result of new information or future events or developments. XTANDI can cause fetal harm when administered to pregnant women. Fatal adverse reactions and modify the dosage as recommended for adverse reactions.

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