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The incidence of amyloid-related imaging abnormalities (ARIA) and infusion-related reactions was consistent with the United States Securities and Exchange Commission. The overall treatment effect of donanemab continued to grow throughout the trial, with the largest differences versus placebo seen at 18 months. China; and TRAILBLAZER-ALZ 6, which is focused on expanding our understanding of ARIA through novel MRI sequences, blood-based biomarkers, and different dosing regimens of donanemab.

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